The movie tells the story of Moses (played by Charlton Heston), a Hebrew who was adopted by an Egyptian princess. As Moses grows up, he learns about his true heritage and decides to lead his people, the Hebrews, out of slavery in Egypt. The film depicts the life of Moses, from his early days as an Egyptian prince to his later life as a leader of the Hebrews, and the receiving of the Ten Commandments from God.

The 1956 Hindi dubbed version of The Ten Commandments was released in India, where the film was dubbed into Hindi to cater to the local audience. The dubbed version was also released in other countries with Hindi-speaking populations.