She is well-known for creating popular lifestyle and comedy reels with her husband, Riteish Deshmukh , often trending on Instagram and YouTube. She hosted the reality show Big Switch (2009) and the game show Ladies vs Gentlemen (2020), with clips frequently viewed online.

Before she conquered Bollywood, Genelia was already a superstar in the South Indian film industries. Her filmography is heavily stacked with Telugu and Tamil hits, where she often played roles that balanced glamour with strong character arcs.

In addition to films, Genelia has also appeared in several TV shows, including:

(2025) : An Aamir Khan starrer where she plays the role of a basketball coach’s wife, Sunita Aurora. Gunmaster G9

(2003) : Her debut film alongside her now-husband, Riteish Deshmukh.

(2006, Telugu) : Her portrayal of the bubbly "Hasini" earned her the Filmfare Award for Best Actress – Telugu .