Sangeetha was born on October 21, 1979, in Chennai, Tamil Nadu. She began her acting career at a young age, making her debut in the Tamil film "Raja Kadhirvelan" in 1992. However, it was her move to Telugu cinema in the late 1990s that catapulted her to fame. Her first Telugu film was "Sankeertana" in 1997, which was followed by a string of successful films that established her as a leading lady in Telugu cinema.